What is Dihydrocodeine 30mg?
The drug dihydrocodeine 30mg is a semi-synthetic opioid painkiller that was developed in Germany in 1908. It was developed during the search for a more effective cough medicine to reduce the spread of airborne infectious diseases such as pertussis, tuberculosis and pneumonia. Its chemical structure is similar to that of codeine.
Dihydrocodeine 30mg is an analgesic painkiller that works by binding certain small areas, called opioid receptors, in your brain and spinal cord to provide you relief from pain.
It stops the pain signals from travelling along the nerves to the brain. It is used to treat severe or chronic pain, including post-operative or severe injury pain or dyspnea or is prescribed as an antitussive.
It commonly comes in as tablets, elixirs, solutions and other oral forms. It also comes in as an injectable solution for administration under the skin or intramuscular administration. It is available only on prescription, and injections should be taken in a hospital only.
Dihydrocodeine’s side effects include drowsiness, dry mouth, nausea, constipation, headache, difficulty urinating, and mild euphoria. It can also impair mental as well as physical abilities to perform hazardous tasks such as driving or operating machinery.
One should not stop taking the medication suddenly as this may cause withdrawal, especially in case you have used it for long or in a high dose.
You can also become addicted to it, specifically when you have a substance use disorder like addiction to drugs or alcohol. To avoid addiction, take the medication only in the prescribed dosage.
Dihydrocodeine is a semi-synthetic opioid analgesic used as an alternative or adjunct to codeine prescribed to treat moderate to severe types of pain such as after an operation or a serious injury, and also cough.
Dihydrocodeine was developed in Germany in 1908 during the international search to find a more effective antitussive agent to help reduce the spread of so many airborne diseases such as tuberculosis, pertussis and pneumonia.
It was approved for medical use in 1948. It is similar in chemical structure to codeine and it’s twice as strong as codeine. Dihydrocodeine is sometimes prescribed in combination with other pain killers such as paracetamol, ibuprofen and aspirin in medicine called co-dydramol. Co-dydramol is available on prescription and also from pharmacies on the advice of a pharmacist.
Dihydrocodeine is available as tablets, solutions, elixirs and other oral forms, it is also available in some countries as an injectable solution for deep subcutaneous and intramural-muscular administration, and also in suppository forms, these suppositories were used in the past.
As with codeine, intravenous administration should be avoided as it could result in anaphylaxis and life-threatening pulmonary oedema. Dihydrocodeine is also the original member and chemical base of several similar semi-synthetic opioids such as acetyldihydrocodeine, Dihydrocodeinone, Enole acetate, dihydrocodeine, nicocodeine and nicodicodeine.
Although dihydrocodeine does not have extremely active metabolites in the form of dihydromorphine and dihydromorphine-6-glucuronide, these metabolites are produced in small amounts and do not have clinically significant effects. Dihydrocodeine works by binding to certain tiny areas called the opioid receptors in your central nervous system (brain and spinal cords)this leads to a decrease in the way you feel pain and your reaction to pain.
However, this product has a risk of abuse and addiction, which can lead to overdose and death, it may also cause severe breathing problems, unusual lightheadedness, severe drowsiness and difficulty waking up. The risk for severe breathing problems is higher when you start this product or if u take the wrong dose. Taking this drug with alcohol or other drugs that can cause drowsiness or breathing problems may lead to very serious side effects including death.
Dihydrocodeine 30mg Tablet
Dihydrocodeine tablet 30 mg is an analgesic painkiller to treat moderate to severe pain. It is prescribed in conditions where an alert patient is desired, like types of arthritis, sciatica, peripheral vascular disease, Paget’s disease, post-herpetic neuralgia, malignant disease and post-operative pain.
When given in recommended doses, dihydrocodeine causes little or no respiratory depression, thus reducing the risk of chest complications when treating post-operative pain.
To reduce the risk of addiction and withdrawal syndrome, a strategy should be put in place after discussing with the patient to end the treatment with dihydrocodeine tablets 30mg. As prolonged use of dihydrocodeine tablets, 30mg may lead to addiction even at therapeutic doses.
The risk of addiction increases if the patient has a history or is suffering from substance misuse disorder or any other mental health disorder.
Dihydrocodeine’s one tablet of 30mg can be given every 4-6 hours to adults and children above the age of 12 years, and one can be given a maximum dose of 6 tablets in 24 hours. Though dosage should be given only as prescribed by a qualified medical practitioner.
Each tablet contains 30mg dihydrocodeine Titrate and each 30mg tablet contains 143.00mg lactose monohydrate. The high end of standard dihydrocodeine dose is 30mg for immediate-release oral tablets.
As an analgesic for the relief of moderate to severe pain, dihydrocodeine 30mg is indicated in all conditions where an alert patient is desired such as arthritis of the spine, chronic rheumatoid arthritis and post-operative pain.
For a single dose of dihydrocodeine 30mg in moderate to severe postoperative pain, the number needed to treat for at least 50% pain relief is 8.1 compared to placebo.
A single 30mg dose of dihydrocodeine is therefore not significant to provide adequate pain relief in post-operative pain. Significantly, more patients have reported adverse effects with dihydrocodeine 30mg than with placebo. To relieve moderate to severe pain, the usual dose for adults and adolescents aged 12 years and over is one 30mg tablet taken every four to six hours as needed to relieve pain.
Taking more than one tablet at a time will not give more pain relief but may increase the risk of side effects. In case you forget to take a dose, take it as soon as you remember and then carry on as before. Always leave at least 4hrs between dose, do not take a double dose to make up for a missed dose.
Dihydrocodeine is often abused recreationally due to the euphoric high that can result from using high doses of the drug. Those who abuse the drug often take between 70mg-500mg at once to achieve the desired effect.
What is Dihydrocodeine vs Codeine
Dihydrocodeine and codeine are both opioids. Dihydrocodeine is a chemical derivative of codeine formed by hydrogenation of the double tie in the main chain of the molecule of codeine.
It produces similar effects to codeine. Codeine is used for treating coughs (antitussive) or to relieve analgesic pain. In contrast, dihydrocodeine is used to treat moderate to severe chronic pains from post-operative surgery, severe injury or dyspnea, or to treat antitussive. Dihydrocodeine should not be taken with painkillers that contain codeine.
Codeine and dihydrocodeine belong to a group of pain relief called “weak opioids” analgesics. These medications are part of the opium family and are similar to morphine and originally come from a part of poppy seeds.
Although called “weak opioids” they are strong pain relief medications. Dihydrocodeine belongs to a class of medications categorized as opioid analgesic. It is a semi-synthetic derivative of codeine. which means it is related to codeine and they have the same activity and effects.
Dihydrocodeine being a much stronger analgesic drug and has a higher euphoric effect on the user and a higher risk of dependence or abuse for the patient talking it. Codeine on the other hand is a food and drug Administration (FDA) that approves opioid analgesic medication that is naturally occurring and found on the poppy plant that is typically prescribed for things such as severe cough and it is used to relieve the symptoms of mild to moderate pain.
When Codeine is used for treating, it acts by changing the way your nervous system and brain respond to that pain. Codeine is selective to the mu receptor, but with a much weaker affinity than morphine. The analgesic properties found in Codeine have been speculated to come from its convention to morphine, although the exact mechanism of the analgesic action is less understood than the more potent members of the opiate family. Codeine is absorbed from the gastrointestinal tract with maximum plasma concentration occurring 60mins after administration.
Codeine is absorbed quickly from the gastrointestinal tract and its first pass through the liver results in very little loss of the drug. This is why Codeine is a common opiate in the relief of pain, the ease of oral administration. Dihydrocodeine in its simple form has a short half-life but longer-acting controlled release tablet one frequently cited reason it never really achieved the prominence its properties warranted as an opiate treatment option was not least because of a largely inaccurate perception that the tablet is crushed and injected.
The most difference between dihydrocodeine and Codeine are primarily within the structure of the two substances, it is also important to talk about their biggest similarity, that is their risk of abuse and addiction. While these two substances may not be the most potent when taken as prescribed.
If taken in excess or more often than needed, you risk the possibility of addiction. After all, both substances are opioids and have a very high likelihood of misuse and dependence. Not only is abuse and addiction to these two substance possible it can also act as a gateway to stronger opioid use. The adverse effect of Codeine and dihydrocodeine are similar to other opioid analgesics; vomiting, constipation, drowsiness and confusion. Other long term effects include dry mouth, dizziness, sweating, headache and restlessness.